Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL5831307

C=CCc1ccc(C(=S)OCC)cc1.OC(=S)c1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
CYP3A4 P08684 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 7/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
ALOX12 P18054 2/20 0.38
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
MAPT P10636 3/20 0.36
CNR2 P34972 1/20 0.35
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
NPC1 O15118 2/20 0.33
GAA P10253 2/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL5831404 0.86 CYP3A4 (0.45) MEN1KMT2ACYP3A4TDP1L3MBTL1
Thiobenzoic Acid SCHEMBL27075762 0.83 ALDH1A1 (0.43) MEN1KMT2AALDH1A1SMN1; SMN2TSHR
Thiobenzoic Acid SCHEMBL17100047 0.83 ALDH1A1 (0.43) MEN1KMT2AALDH1A1SMN1; SMN2TSHR
SCHEMBL3031149 0.80 ALDH1A1 (0.45) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL5830966 0.78 CYP4F2 (0.40) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL9041640 0.78 ALDH1A1 (0.47) MEN1KMT2AALDH1A1SMN1; SMN2TSHR
SCHEMBL1641519 0.78 ALDH1A1 (0.47) MEN1KMT2AALDH1A1SMN1; SMN2TSHR
Thiobenzoic Acid SCHEMBL5534429 0.77 ALDH1A1 (0.46) MEN1KMT2AALDH1A1SMN1; SMN2TSHR
Thiobenzoic Acid SCHEMBL29151609 0.77 ALDH1A1 (0.40) MEN1KMT2AALDH1A1SMN1; SMN2TSHR
SCHEMBL5832000 0.76 ALDH1A1 (0.43) MEN1KMT2ACYP3A4TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed