Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL5831404

C=CCc1ccc(C(=S)OC)cc1.OC(=S)c1ccccc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 5/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALOX5 P09917 1/20 0.38
AR P10275 1/20 0.38
PTGS1 P23219 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL5831307 0.86 MEN1 (0.40) CYP3A4TDP1L3MBTL1MEN1KMT2A
SCHEMBL3031149 0.82 ALDH1A1 (0.45) CYP3A4TDP1L3MBTL1MEN1KMT2A
Thiobenzoic Acid SCHEMBL10902274 0.81 HPGD (0.44) CYP3A4TDP1L3MBTL1MEN1KMT2A
Thiobenzoic Acid SCHEMBL2320796 0.80 HPGD (0.47) CYP3A4TDP1L3MBTL1MEN1KMT2A
Thiobenzoic Acid SCHEMBL8082926 0.80 ALDH1A1 (0.41) CYP3A4L3MBTL1MEN1KMT2AALDH1A1
Thiobenzoic Acid SCHEMBL9789964 0.76 ESR1 (0.44) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL812710 0.75 TSHR (0.52) CYP3A4TDP1L3MBTL1MEN1KMT2A
Thiobenzoic Acid SCHEMBL9789868 0.74 CES2 (0.46) MEN1KMT2AALDH1A1TSHRALOX12
SCHEMBL8060229 0.73 CYP3A4 (0.45) CYP3A4TDP1L3MBTL1MEN1KMT2A
Styrene SCHEMBL27686133 0.73 ALDH1A1 (0.52) CYP3A4TDP1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed