SCHEMBL5831388

SCHEMBL5831388

C=CCc1ccc(S)c(C(=O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.46
MAPT P10636 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
GABRA1 P14867 2/20 0.44
CNR1 P21554 2/20 0.44
CNR2 P34972 2/20 0.44
GABRB2 P47870 2/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH2 P05091 1/20 0.44
AKR1B1 P15121 1/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PPARA Q07869 2/20 0.42
HDAC8 Q9BY41 1/20 0.41
PTGS1 P23219 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831661 0.86 XDH (0.46) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL15006288 0.84 XDH (0.50) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL7061099 0.82 XDH (0.48) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL979252 0.81 KLKB1 (0.65) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL30407861 0.80 KLKB1 (0.62) MAPTALDH1A1GAAKDM4EHPGD
SCHEMBL5832225 0.79 ALDH1A1 (0.66) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL6036597 0.79 XDH (0.46) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL663578 0.79 ALDH1A1 (0.52) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL9273645 0.79 MAPT (0.56) XDHMAPTALDH1A1MEN1KMT2A
SCHEMBL10774122 0.77 XDH (0.47) XDHMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed