SCHEMBL5832060

SCHEMBL5832060

CC1(C)CNCCN1CCCO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.32
SOS2 Q07890 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801060 0.89 SOS1 (0.34) SOS1SOS2
Hydrochloric Acid SCHEMBL20660386 0.87 SOS1 (0.33) SOS1SOS2
SCHEMBL9801221 0.81 SOS1 (0.32) SOS1SOS2
SCHEMBL27613283 0.80 GNAO1 (0.39) SOS1SOS2
SCHEMBL7449892 0.79 SOS1 (0.35) SOS1SOS2
SCHEMBL6380836 0.77 SOS1 (0.34) SOS1SOS2
Bromide SCHEMBL8997309 0.76 SOS1 (0.39) SOS1SOS2
SCHEMBL21038731 0.74 MEN1 (0.33) SOS1SOS2
SCHEMBL8406319 0.74 CARM1 (0.36) SOS1SOS2
Piperazine SCHEMBL28225897 0.74 SOS1 (0.32) SOS1SOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100347169-C Quinazoline derivatives ASTRAZENECA AB (SE) 2007-11-07 CN disclosed
US-7115615-B2 Quinazoline derivatives ASTRAZENECA (SE) 2006-10-03 US disclosed
CN-1471527-A Quinazoline derivatives 2004-01-28 CN disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed