SCHEMBL9801060

SCHEMBL9801060

CC1(C)CNCCN1CCO

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.34
SOS2 Q07890 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20660386 0.98 SOS1 (0.33) SOS1SOS2
SCHEMBL5832060 0.89 SOS1 (0.32) SOS1SOS2
SCHEMBL7449892 0.82 SOS1 (0.35) SOS1SOS2
SCHEMBL8142778 0.81 SOS1 (0.32) SOS1SOS2
SCHEMBL6380836 0.80 SOS1 (0.34) SOS1SOS2
SCHEMBL8406319 0.77 CARM1 (0.36) SOS1SOS2
SCHEMBL21038731 0.77 MEN1 (0.33) SOS1SOS2
Piperazine SCHEMBL28225897 0.77 SOS1 (0.32) SOS1SOS2
SCHEMBL9801221 0.77 SOS1 (0.32) SOS1SOS2
SCHEMBL9801465 0.77 TSHR (0.36) SOS1SOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075063-A The composition of moisture-curable 莫门蒂夫性能材料股份有限公司 2017-08-18 CN claimed
CN-101168601-B Crosslinkers for improving stability of polyurethane foams AIR PROD & CHEM 2013-03-06 CN claimed
CN-101168601-A Crosslinkers for improving stability of polyurethane foams AIR PROD & CHEM (US) 2008-04-30 CN claimed
EP-3654968-B1 METALLO-BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF MERCK SHARP & DOHME LLC (US) 2023-08-16 EP disclosed
US-11207312-B2 Metallo-beta-lactamase inhibitors and methods of use thereof MERCK SHARP & DOHME CORP. (US) 2021-12-28 US disclosed
US-20200281913-A1 Metallo-Beta-Lactamase Inhibitors and Methods of Use Thereof MERCK SHARP & DOHME CORP. (US) 2020-09-10 US disclosed
CN-108885421-A charging roller 株式会社普利司通 2018-11-23 CN disclosed
CN-108604073-A Conductive roll and its manufacturing method 株式会社普利司通 2018-09-28 CN disclosed
CN-104968699-B Conductive polymer material, method for producing conductive polymer material, and image forming apparatus member 株式会社普利司通 2018-09-11 CN disclosed
CN-107935943-A Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof 中国科学院理化技术研究所 2018-04-20 CN disclosed
CN-107272377-A Developer roll 株式会社普利司通 2017-10-20 CN disclosed
CN-101681140-A electrically conductive roller BRIDGESTONE CORP 2010-03-24 CN disclosed
CN-101548246-A Conductive elastic roller and image forming apparatus including the same BRIDGESTONE CORP (JP) 2009-09-30 CN disclosed
CN-100489680-C Conductive roller and image forming apparatus comprising the same BRIDGESTONE CORP (JP) 2009-05-20 CN disclosed
CN-101182860-A Electrical conductive roller and imaging apparatus comprising the same BRIDGESTONE CORP (JP) 2008-05-21 CN disclosed
CN-101168601-A Crosslinkers for improving stability of polyurethane foams AIR PROD & CHEM (US) 2008-04-30 CN disclosed
CN-101013291-A Conductive elastic roller and image forming apparatus comprising the same BRIDGESTONE CORP (JP) 2007-08-08 CN disclosed
CN-1963685-A Developing roller and imaging apparatus comprising the same BRIDGESTONE CORP (JP) 2007-05-16 CN disclosed
CN-1912767-A Conductive roller and image forming apparatus comprising the same BRIDGESTONE CORP (JP) 2007-02-14 CN disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200281913-A1 Metallo-Beta-Lactamase Inhibitors and Methods of Use Thereof MLX, MMP12, SLC11A2 SOS1 916/4885SOS2 1738/4885
US-11207312-B2 Metallo-beta-lactamase inhibitors and methods of use thereof MLX, MMP12, SLC11A2 SOS1 916/4885SOS2 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.