SCHEMBL5832429

SCHEMBL5832429

C=CCc1cccc(C(=O)O)c1S

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.47
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
MAPT P10636 4/20 0.43
ALDH1A1 P00352 4/20 0.43
POLB P06746 1/20 0.43
HDAC8 Q9BY41 1/20 0.41
KMT2A Q03164 3/20 0.40
HMGB1 P09429 1/20 0.40
TSHR P16473 1/20 0.40
ALOX15 P16050 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27083018 0.83 FOLH1 (0.55) FOLH1GABRA1GABRB2MAPTALDH1A1
SCHEMBL89060 0.83 FOLH1 (0.55) FOLH1GABRA1GABRB2MAPTALDH1A1
Ammonia Solution, Strong SCHEMBL16531812 0.82 FOLH1 (0.53) FOLH1GABRA1GABRB2MAPTALDH1A1
Potassium SCHEMBL16531822 0.82 FOLH1 (0.53) FOLH1GABRA1GABRB2MAPTALDH1A1
Ammonia Solution, Strong SCHEMBL9940062 0.82 FOLH1 (0.53) FOLH1GABRA1GABRB2MAPTALDH1A1
SCHEMBL11094883 0.82 FOLH1 (0.53) FOLH1GABRA1GABRB2MAPTALDH1A1
Phosphine SCHEMBL28264956 0.82 FOLH1 (0.53) FOLH1GABRA1GABRB2MAPTALDH1A1
Hydrochloric Acid SCHEMBL7974299 0.82 FOLH1 (0.53) FOLH1GABRA1GABRB2MAPTALDH1A1
SCHEMBL30365997 0.81 GABRA1 (0.59) FOLH1GABRA1GABRB2MAPTALDH1A1
SCHEMBL1137942 0.81 GABRA1 (0.46) FOLH1GABRA1GABRB2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20050004318-A1 Curable composition OHSHIRO NOBUAKI (JP) 2005-01-06 US disclosed
EP-1452550-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-09-01 EP disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed
EP-0219901-B1 PERFUME COMPOSITIONS AND PERFUMED PRODUCTS WHICH CONTAIN AN ALKYL 2-MERCAPTOBENZOATE AS BASIC COMPONENT NAARDEN INTERNATIONAL N.V. (NL) 1989-04-19 EP disclosed
EP-0219901-A1 Perfume compositions and perfumed products which contain an alkyl 2-mercaptobenzoate as basic component NAARDEN INTERNATIONAL N.V. (NL) 1987-04-29 EP disclosed