Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27247090 | 0.83 | PPARG (0.52) | PPARGPPARAPPARDIDERECQL | |
| SCHEMBL21115189 | 0.80 | HTR6 (0.44) | NAMPTRECQLALDH1A1LMNAMAPT | |
| SCHEMBL4035724 | 0.78 | ALDH1A1 (0.52) | NAMPTRECQLALDH1A1LMNAMAPT | |
| SCHEMBL5833331 | 0.77 | RECQL (0.43) | NAMPTRECQLALDH1A1LMNAMAPT | |
| SCHEMBL17422763 | 0.77 | PPARG (0.44) | PPARGPPARAPPARDIDERECQL | |
| SCHEMBL16235707 | 0.77 | PPARG (0.59) | PPARGPPARAPPARDLMNASRC | |
| SCHEMBL17556132 | 0.77 | PPARG (0.59) | PPARGPPARAPPARDLMNASRC | |
| SCHEMBL4271243 | 0.77 | RECQL (0.57) | NAMPTRECQLALDH1A1LMNAMAPT | |
| SCHEMBL4273734 | 0.77 | MAPT (0.57) | NAMPTRECQLALDH1A1LMNAMAPT | |
| SCHEMBL10552139 | 0.76 | PIK3C3 (0.48) | PPARGPPARAPPARDIDERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732566-A2 | 6-AZAINDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097129-A2 | 6-AZAINDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-20 | — | — | WO | disclosed |