Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275083 | 0.91 | RAB9A (0.56) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL13660724 | 0.89 | PDGFRB (0.44) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL20742915 | 0.71 | PDGFRB (0.68) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL7688984 | 0.70 | SRD5A2 (0.51) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL4266872 | 0.70 | GABRP (0.53) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL20762579 | 0.69 | PDGFRB (0.61) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL4281599 | 0.69 | GABRP (0.54) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL20742929 | 0.67 | SRD5A2 (0.53) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL20762061 | 0.66 | PDGFRB (0.73) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E | |
| SCHEMBL187522 | 0.65 | SRD5A2 (0.76) | PDGFRBPDGFRASRD5A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732566-A2 | 6-AZAINDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | claimed |
| WO-2005097129-A2 | 6-AZAINDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-20 | — | — | WO | claimed |
| EP-1732566-A2 | 6-AZAINDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097129-A2 | 6-AZAINDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-20 | — | — | WO | disclosed |