Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408895 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL22352622 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL1263892 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL29054777 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL3905928 | 0.98 | — | — | |
| SCHEMBL2541950 | 0.90 | — | — | |
| SCHEMBL28627801 | 0.88 | — | — | |
| SCHEMBL5136503 | 0.87 | ALDH1A1 (0.70) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL11491818 | 0.87 | ALDH1A1 (0.70) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL11492305 | 0.87 | ALDH1A1 (0.70) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199949-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2006-09-07 | — | — | US | disclosed |
| US-7008798-B2 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2006-03-07 | — | — | US | disclosed |
| US-6989275-B2 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2006-01-24 | — | — | US | disclosed |
| US-6956032-B1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2005-10-18 | — | — | US | disclosed |
| US-20020146736-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY | 2002-10-10 | — | — | US | disclosed |
| US-20020142340-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY | 2002-10-03 | — | — | US | disclosed |
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6225050-B1 | LABELING PROTEINS, CELLS, NUCLEIC ACIDS, SUGARS, CARBOHYDRATES, OR MIXTURES USING CYANINE DYE WHICH REACTS WITH AMINE, SULFHYDRYL, OR HYDROXY GROUPS OF COMPONENT | CARNEGIE MELLON UNIVERSITY | 2001-05-01 | — | — | US | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6048982-A | OXAZOLE, THIAZOLE OR IMIDAZOLE CYANINE DYES FOR LABELS | CARNEGIE MELLON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0898596-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | Amersham Pharmacia Biotech UK Limited (GB) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040104-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-10-30 | — | — | WO | disclosed |
| US-4182773-A | Novel prostaglandin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142340-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | SHBG, IK, PTMS | ALDH1A1 2640/4885LMNA 1642/4885APOBEC3A 3407/4885 |
| US-20060199949-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | SHBG, IK, PTMS | ALDH1A1 2640/4885LMNA 1642/4885APOBEC3A 3407/4885 |
| US-20020146736-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | SHBG, IK, PTMS | ALDH1A1 2640/4885LMNA 1642/4885APOBEC3A 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.