Benzoin

Benzoin

SCHEMBL5833429

O=C(c1ccccc1)[C@H](O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 1.00
CES1 P23141 4/20 1.00
LMNA P02545 3/20 1.00
ALDH1A1 P00352 2/20 0.67
KDM4E B2RXH2 1/20 0.67
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
MAPK1 P28482 1/20 0.62
HPGD P15428 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.47
MDM2 Q00987 1/20 0.47
CYP2D6 P10635 1/20 0.46
SRC P12931 1/20 0.46
DAO P14920 1/20 0.46
TSHR P16473 1/20 0.46
NAPRT Q6XQN6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoin SCHEMBL27696284 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL10665271 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL901258 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL28120851 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL145 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL2025536 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL28790122 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL11590328 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL28834400 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL7766715 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111889087-B Preparation and application of pyridine ionic liquid functionalized beta-cyclodextrin silica gel chromatographic stationary phase 中国科学院兰州化学物理研究所 2023-04-14 CN claimed
EP-4658802-A1 PROCESS FOR MAKING DRIMANE ALDEHYDES Firmenich SA (CH) 2025-12-10 EP disclosed
CN-112823179-B Photocurable polymer, photocurable polymer composition, and photolithography process including the same 索尔维特殊聚合物美国有限责任公司 2025-04-08 CN disclosed
WO-2024160757-A1 PROCESS FOR MAKING DRIMANE ALDEHYDES FIRMENICH SA (CH) 2024-08-08 WO disclosed
CN-111889087-B Preparation and application of pyridine ionic liquid functionalized beta-cyclodextrin silica gel chromatographic stationary phase 中国科学院兰州化学物理研究所 2023-04-14 CN disclosed
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2020-06-16 US disclosed
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN TECHNICAL UNIVERSITY OF DARMSTADT (DE) 2019-06-27 US disclosed
WO-2017198717-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2017-11-23 WO disclosed
US-8513442-B2 Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions THE UNIVERSITY OF CHICAGO (US) 2013-08-20 US disclosed
US-7230125-B1 Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions THE UNIVERSITY OF CHICAGO (US) 2007-06-12 US disclosed
US-7045334-B2 Nucleotide sequence encoding a benzaldehyde lyase, and process for stereoselectively synthesizing 2-hydroxyketones Forschungszentrum Jülich GmbH (DE) 2006-05-16 US disclosed
US-20040014182-A1 Nucleotide sequence encoding a benzaldehyde lyase, and process for stereoselectively synthesizing 2-hydroxyketones FORSCHUNGSZENTRUM JULICH GMBH (DE) 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN ALDOA, TALDO1, DERA CES2 1892/4885CES1 376/4885LMNA 2595/4885
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein ALDOA, TALDO1, DERA CES2 1892/4885CES1 376/4885LMNA 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.