Benzoin

Benzoin

SCHEMBL2025536

O=C(c1ccccc1)[C@@H](O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 1.00
CES1 P23141 4/20 1.00
LMNA P02545 3/20 1.00
ALDH1A1 P00352 2/20 0.67
KDM4E B2RXH2 1/20 0.67
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
MAPK1 P28482 1/20 0.62
HPGD P15428 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.47
MDM2 Q00987 1/20 0.47
CYP2D6 P10635 1/20 0.46
SRC P12931 1/20 0.46
DAO P14920 1/20 0.46
TSHR P16473 1/20 0.46
NAPRT Q6XQN6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoin SCHEMBL27696284 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL10665271 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL901258 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL28120851 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL5833429 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL145 1.00 CES2 (1.00) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL28790122 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL11590328 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL28834400 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL7766715 0.98 CES2 (0.95) CES2CES1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004028548-A2 INHIBITORS OF THE NITRIX OXIDE SYNTHASE III (NOS III) AS NEUROPROTECTIVE AGENTS CARBOMER, INC. (US) 2004-04-08 WO claimed
US-20040063612-A1 Neuroprotective agents CARBOMER, INC. 2004-04-01 US claimed
EP-4658802-A1 PROCESS FOR MAKING DRIMANE ALDEHYDES Firmenich SA (CH) 2025-12-10 EP disclosed
WO-2024160757-A1 PROCESS FOR MAKING DRIMANE ALDEHYDES FIRMENICH SA (CH) 2024-08-08 WO disclosed
EP-4396209-A1 METHODS OF PRODUCING HUMAN MILK OLIGOSACCHARIDES AND COMPOSITIONS THEREOF Amyris, Inc. (US) 2024-07-10 EP disclosed
US-11760776-B2 Methods for modulating protein expression in microorganisms ORTERON (T.O) LTD. (IL) 2023-09-19 US disclosed
WO-2023034973-A1 METHODS OF PRODUCING HUMAN MILK OLIGOSACCHARIDES AND COMPOSITIONS THEREOF Amyris, Inc. (US) 2023-03-09 WO disclosed
CN-108250042-B Preparation method of (S) - (-) -1,1, 2-triphenyl-1, 2-glycol 常州沃腾化工科技有限公司 2021-03-02 CN disclosed
US-20190256553-A1 NOVEL METHODS FOR MODULATING PROTEIN EXPRESSION IN MICROORGANISMS ORTERON (T.O) LTD. (IL) 2019-08-22 US disclosed
US-9198451-B2 Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners SYMRISE AG (DE) 2015-12-01 US disclosed
EP-2220945-B1 Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners SYMRISE AG (DE) 2013-03-27 EP disclosed
WO-2004028548-A2 INHIBITORS OF THE NITRIX OXIDE SYNTHASE III (NOS III) AS NEUROPROTECTIVE AGENTS CARBOMER, INC. (US) 2004-04-08 WO disclosed
US-20040063612-A1 Neuroprotective agents CARBOMER, INC. 2004-04-01 US disclosed
US-20040014182-A1 Nucleotide sequence encoding a benzaldehyde lyase, and process for stereoselectively synthesizing 2-hydroxyketones FORSCHUNGSZENTRUM JULICH GMBH (DE) 2004-01-22 US disclosed
JP-2002199882-A OXIDOREDUCTASE DERIVED FROM MERIONES UNGUICULATUS, GENE ENCODING THE ENZYME, TRANSFORMANT CONTAINING THE ENZYME GENE AND METHOD FOR PRODUCING THE ENZYME ARAKAWA CHEM IND CO LTD 2002-07-16 JP disclosed
JP-2002171985-A OXIDOREDUCTASE, GENE ENCODING THE ENZYME, TRANSFORMANT CONTAINING THE ENZYME GENE AND METHOD FOR PRODUCING THE ENZYME ARAKAWA CHEM IND CO LTD 2002-06-18 JP disclosed
US-6384228-B2 EPIBATIDINE; ANALGESICS; ANIMAL EXTRACTS NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-05-07 US disclosed
JP-2002065267-A OXIDOREDUCTASE, GENE ENCODING THE SAME AND CLONING OF THE GENE ARAKAWA CHEM IND CO LTD 2002-03-05 JP disclosed
US-20020010339-A1 METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF NIHON MEDI-PHYSICS CO., LTD. (JP) 2002-01-24 US disclosed
EP-0190815-A2 Process for producing aromatic diols CELANESE CORPORATION (US) 1986-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010339-A1 METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF DHPS, ALAD, HAAO CES2 742/4885CES1 705/4885LMNA 2799/4885
US-20040063612-A1 Neuroprotective agents GAP43, NLN, NOS3 CES2 610/4885CES1 877/4885LMNA 1081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.