Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238795 | 0.86 | PTPN1 (0.57) | KDM4EALDH1A1HDAC8PLOD2PTPN1 | |
| SCHEMBL710254 | 0.86 | PTPN1 (0.57) | KDM4EALDH1A1HDAC8PLOD2PTPN1 | |
| SCHEMBL10456257 | 0.84 | PTPN1 (0.56) | KDM4EALDH1A1HDAC8PLOD2PTPN1 | |
| SCHEMBL28103343 | 0.84 | PTPN1 (0.56) | KDM4EALDH1A1HDAC8PLOD2PTPN1 | |
| SCHEMBL14497162 | 0.80 | PLOD2 (0.42) | KDM4EALDH1A1GAAHDAC1HDAC7 | |
| SCHEMBL2697287 | 0.80 | MEN1 (0.50) | KDM4EALDH1A1HDAC1HDAC7HDAC8 | |
| SCHEMBL1152905 | 0.79 | PLA2G2D (0.62) | KDM4EALDH1A1GAAHDAC1HDAC7 | |
| SCHEMBL6568049 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1GAAHDAC1HDAC7 | |
| SCHEMBL11629513 | 0.76 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAPTPN1MTNR1A | |
| SCHEMBL29215273 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1GAAPTPN1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417216-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | Inbio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz Gbr (DE) | 2012-02-15 | — | — | EP | claimed |
| WO-2010115503-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | INBIO PROF. JÜRGEN BÜDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ GBR (DE) | 2010-10-14 | — | — | WO | claimed |