Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873938 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11284346 | 0.81 | POLB (0.47) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29822784 | 0.81 | GRIN2D (0.47) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11251266 | 0.79 | ALDH1A1 (0.44) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1520224 | 0.78 | GAA (0.47) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL11255459 | 0.78 | ALDH1A1 (0.43) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10515947 | 0.78 | P2RX7 (0.44) | P2RX7ALDH1A1GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL11554236 | 0.78 | HDAC3 (0.47) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| Methylamine SCHEMBL11262298 | 0.76 | GRIN2D (0.46) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9227585 | 0.74 | NPC1 (0.52) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109329-B2 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC | 2006-09-19 | — | — | US | disclosed |