Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066485 | 0.84 | TP53 (0.44) | TP53ALDH1A1ALOX12HPGDALOX15 | |
| SCHEMBL27850999 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ALOX12HPGDALOX15CASP1 | |
| SCHEMBL6989028 | 0.81 | TDP1 (0.54) | ALDH1A1ALOX12HPGDALOX15CASP1 | |
| SCHEMBL19606967 | 0.79 | LOXL2 (0.43) | ALDH1A1TDP1MEN1LMNAHTT | |
| SCHEMBL18387802 | 0.79 | GFER (0.50) | ALDH1A1TAAR1TDP1MAPTCYP2A6 | |
| SCHEMBL24143907 | 0.79 | KCNH2 (0.44) | SIGMAR1HPGDTAAR1KCNH2AOC3 | |
| SCHEMBL28358189 | 0.79 | HRH3 (0.40) | ALDH1A1ALOX12HPGDALOX15CASP1 | |
| SCHEMBL13545891 | 0.78 | TDP1 (0.50) | ALDH1A1ALOX12HPGDALOX15CASP1 | |
| SCHEMBL18231464 | 0.78 | TAAR1 (0.50) | ALDH1A1ALOX12HPGDALOX15CASP1 | |
| SCHEMBL11483933 | 0.77 | TDP1 (0.43) | TP53SIGMAR1ALDH1A1ALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2628744-B1 | Silicon-containing surface modifier, resist underlayer film composition containing this, and patterning process | SHINETSU CHEMICAL CO (JP) | 2016-11-30 | — | — | EP | disclosed |
| EP-2540780-B1 | Composition for forming resist underlayer film and patterning process using the same | SHINETSU CHEMICAL CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-7056935-B2 | Rotamase enzyme activity inhibitors | GPI NIL HOLDINGS, INC. (US) | 2006-06-06 | — | — | US | disclosed |