Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778009 | 0.87 | MPI (0.42) | MPITDP1MEN1KMT2AGAA | |
| SCHEMBL25930814 | 0.85 | MPI (0.40) | MPITDP1MEN1KMT2AGAA | |
| SCHEMBL25930761 | 0.83 | MPI (0.40) | MPITDP1MEN1KMT2AGAA | |
| SCHEMBL9750159 | 0.80 | MPI (0.38) | MPITDP1MEN1KMT2A | |
| SCHEMBL5850674 | 0.79 | MPI (0.37) | MPITDP1KDM4EALDH1A1LMNA | |
| SCHEMBL17472378 | 0.78 | MEN1 (0.43) | TDP1MEN1KMT2AGAAPKM | |
| SCHEMBL4603122 | 0.78 | MPI (0.50) | MPITDP1MEN1KMT2AGAA | |
| SCHEMBL9735859 | 0.78 | ESR1 (0.38) | MPITDP1KDM4EALDH1A1LMNA | |
| SCHEMBL9736230 | 0.78 | ESR1 (0.38) | MPITDP1KDM4EALDH1A1LMNA | |
| SCHEMBL9737334 | 0.78 | ESR1 (0.38) | MPITDP1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20060199949-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2006-09-07 | — | — | US | disclosed |
| US-7008798-B2 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2006-03-07 | — | — | US | disclosed |
| US-6989275-B2 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2006-01-24 | — | — | US | disclosed |
| US-6956032-B1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 2005-10-18 | — | — | US | disclosed |
| US-20020146736-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY | 2002-10-10 | — | — | US | disclosed |
| US-20020142340-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY | 2002-10-03 | — | — | US | disclosed |
| US-6225050-B1 | LABELING PROTEINS, CELLS, NUCLEIC ACIDS, SUGARS, CARBOHYDRATES, OR MIXTURES USING CYANINE DYE WHICH REACTS WITH AMINE, SULFHYDRYL, OR HYDROXY GROUPS OF COMPONENT | CARNEGIE MELLON UNIVERSITY | 2001-05-01 | — | — | US | disclosed |
| US-6048982-A | OXAZOLE, THIAZOLE OR IMIDAZOLE CYANINE DYES FOR LABELS | CARNEGIE MELLON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-5627027-A | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | CARNEGIE MELLON UNIVERSITY (US) | 1997-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142340-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | SHBG, IK, PTMS | MPI 2306/4885TDP1 3605/4885MEN1 919/4885 |
| US-20060199949-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | SHBG, IK, PTMS | MPI 2306/4885TDP1 3605/4885MEN1 919/4885 |
| US-20020146736-A1 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods | SHBG, IK, PTMS | MPI 2306/4885TDP1 3605/4885MEN1 919/4885 |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | POLI, POLL, POLRMT | MPI 476/4885TDP1 97/4885MEN1 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.