Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833776 | 0.83 | MAOB (0.36) | MAOBMAOAF10 | |
| SCHEMBL5833640 | 0.73 | MAOB (0.34) | MAOBMAOAF10 | |
| SCHEMBL5833969 | 0.72 | MAOA (0.36) | MAOBMAOAF10 | |
| SCHEMBL5833993 | 0.71 | MAOB (0.34) | MAOBMAOAF10 | |
| SCHEMBL5834193 | 0.71 | MAOB (0.36) | MAOBMAOAF10 | |
| SCHEMBL5833669 | 0.71 | MAOA (0.40) | MAOBMAOAF10 | |
| SCHEMBL5833798 | 0.70 | MAOB (0.34) | MAOBMAOAF10 | |
| SCHEMBL5834009 | 0.69 | MAOB (0.34) | MAOBMAOAF10 | |
| SCHEMBL5834205 | 0.69 | MAOB (0.35) | MAOBMAOAF10 | |
| Hydrochloric Acid SCHEMBL5833221 | 0.62 | MAOA (0.36) | MAOBMAOAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087629-B2 | Useful activity against Gram-positive pathogens and, in particular, against various strains exhibiting resistance to vancomycin and against E. faecium strains resistant to both aminoglycosides and clinically used beta-lactams | ASTRAZENECA AB (SE) | 2006-08-08 | — | — | US | disclosed |