SCHEMBL5834741

SCHEMBL5834741

CC(C)CC1C(=O)OC(C)(C)OC1=O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PTPN1 P18031 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
PIK3CD O00329 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
BACE1 P56817 1/20 0.30
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19857350 0.81 GLA (0.41) GLANPSR1PTPN1BACE1
SCHEMBL3080655 0.79 GLA (0.40) GLANPSR1PTPN1L3MBTL1PIK3CD
SCHEMBL8163132 0.77 GLA (0.47) GLANPSR1PTPN1BACE1MDM2
SCHEMBL11597555 0.75
SCHEMBL6059323 0.75 GLA (0.50) GLANPSR1PTPN1BACE1MDM2
SCHEMBL4480703 0.74 GLA (0.43) GLANPSR1
SCHEMBL9193829 0.74 LMNA (0.37) GLANPSR1PTPN1
SCHEMBL25168789 0.73 ALDH1A1 (0.36) GLANPSR1PTPN1L3MBTL1
SCHEMBL1414402 0.73 ALDH1A1 (0.36) GLANPSR1PTPN1L3MBTL1
SCHEMBL1414401 0.73 ALDH1A1 (0.36) GLANPSR1PTPN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122193-B1 Retro peptides, antibodies thereto and their uses for vaccination and in vitro diagnosis BIOMERIEUX S.A. (FR) 2006-10-17 US disclosed
US-6455244-B1 IMMUNOASSAY USING PEPTIDE DERIVED FROM FOOT-AND-MOUTH DISEASE PROTEIN, INFLUENZA PROTEIN, HISTONE PROTEIN, OR AUTOIMMUNE PROTEIN SSA/RO BIOMERIEUX S.A. (FR) 2002-09-24 US disclosed
EP-0578849-B1 Process for the preparation of 1,3-dioxane-4,6-dione derivates BIOGAL GYOGYSZERGYAR (HU) 1995-05-17 EP disclosed
US-5414108-A From a Meldrum's acid derivative BIOGAL GYOGYSZERGRAR (HU) 1995-05-09 US disclosed
US-5350872-A Decyclization and decarboxylation of a 1,3-dioxane-4,6-dione BIOGAL GYOGYSZERGRAR (HU) 1994-09-27 US disclosed
EP-0578849-A1 Process for the preparation of 1,3-dioxane-4,6-dione derivates BIOGAL GYOGYSZERGYAR (HU) 1994-01-19 EP disclosed
EP-0578850-A1 Process for the preparation of carboxylic acids and derivatives of them BIOGAL GYOGYSZERGYAR (HU) 1994-01-19 EP disclosed