Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28723968 | 0.88 | ESR2 (0.52) | ESR2BACE1MAOAMAOBPDE4B | |
| SCHEMBL2860153 | 0.88 | ESR2 (0.52) | ESR2BACE1MAOAMAOBPDE4B | |
| SCHEMBL29836013 | 0.83 | ESR2 (0.52) | ESR2BACE1MAOAMAOBPDE4B | |
| SCHEMBL1513631 | 0.83 | ESR2 (0.52) | ESR2BACE1MAOAMAOBPDE4B | |
| SCHEMBL2864098 | 0.83 | BACE1 (0.60) | ESR2BACE1MAOAMAOBPDE4B | |
| Hydrogen Peroxide SCHEMBL28104708 | 0.83 | ESR2 (0.50) | ESR2BACE1MAOAMAOBALOX5 | |
| SCHEMBL27734232 | 0.81 | ESR2 (0.53) | ESR2BACE1MAOAMAOBPDE4B | |
| SCHEMBL128036 | 0.80 | ESR2 (0.47) | ESR2BACE1PDE4BALOX5ALDH1A1 | |
| Phenol SCHEMBL5340750 | 0.80 | ESR2 (0.53) | ESR2BACE1PDE4BALOX5ALDH1A1 | |
| SCHEMBL29289442 | 0.80 | PDE4B (0.46) | ESR2BACE1PDE4BPTPN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | disclosed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | ALPP, TYR, RB1 | ESR2 261/4885BACE1 4342/4885MAOA 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.