SCHEMBL5835220

SCHEMBL5835220

Nc1ccccc1SCC(O)CO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
POLB P06746 1/20 0.46
MAPT P10636 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
APOBEC3G Q9HC16 1/20 0.45
HSD17B10 Q99714 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
BACE1 P56817 2/20 0.39
GSTP1 P09211 1/20 0.38
GSTM2 P28161 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23120089 0.88 BACE1 (0.42) MEN1KMT2AMAPTAPOBEC3GCA1
SCHEMBL29594498 0.88 BACE1 (0.42) MEN1KMT2AMAPTAPOBEC3GCA1
SCHEMBL976855 0.83 MEN1 (0.52) MEN1KMT2APOLBMAPTNPSR1
SCHEMBL30832932 0.83 MEN1 (0.52) MEN1KMT2APOLBMAPTNPSR1
SCHEMBL11096023 0.83 MEN1 (0.52) MEN1KMT2APOLBMAPTNPSR1
SCHEMBL11097583 0.80 MEN1 (0.50) MEN1KMT2APOLBMAPTNPSR1
SCHEMBL10432986 0.79 BACE1 (0.59) MEN1KMT2APOLBMAPTHSD17B10
SCHEMBL11097562 0.78 KMT2A (0.48) MEN1KMT2APOLBMAPTNPSR1
Glycerin SCHEMBL9706702 0.77 CYP3A4 (0.53) MEN1KMT2AMAPTNPSR1APOBEC3G
SCHEMBL11592728 0.76 HSD17B10 (0.48) MEN1KMT2APOLBMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7029762-B2 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2006-04-18 US disclosed
US-7011895-B2 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2006-03-14 US disclosed
US-20050037228-A1 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2005-02-17 US disclosed
US-20050025991-A1 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2005-02-03 US disclosed