Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Questiomycin B SCHEMBL28074074 | 0.86 | ALOX15 (0.65) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Aniline SCHEMBL27572633 | 0.82 | TSHR (0.55) | CYP3A4ALDH1A1LMNATSHRCYP1A2 | |
| SCHEMBL10693501 | 0.80 | FDPS (0.38) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Glycerin SCHEMBL28051395 | 0.80 | HDAC3 (0.39) | ALOX15SMN1; SMN2ALDH1A1LMNACYP1A2 | |
| Anthranilic Acid SCHEMBL1672125 | 0.80 | MAPT (0.48) | CYP3A4ALOX15CASP7SMN1; SMN2ALDH1A1 | |
| Glycerin SCHEMBL4965821 | 0.78 | ALDH1A1 (0.53) | CYP3A4ALOX15CASP1SMN1; SMN2ALDH1A1 | |
| Naphthalene SCHEMBL28132028 | 0.78 | LMNA (0.53) | ALDH1A1LMNATSHRCYP1A2KDM4E | |
| SCHEMBL27830279 | 0.77 | TSHR (0.33) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL5835220 | 0.77 | MEN1 (0.54) | CYP3A4ALOX15SMN1; SMN2ALDH1A1LMNA | |
| Catechol SCHEMBL27780229 | 0.76 | ALDH1A1 (0.56) | CYP3A4ALOX15SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022638-A1 | PERILIPIN | THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1992-12-23 | — | — | WO | disclosed |