Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107219 | 0.80 | NPSR1 (0.45) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL1674865 | 0.75 | NPSR1 (0.41) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL2458394 | 0.75 | SIRT2 (0.58) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL21356606 | 0.75 | DGAT1 (0.51) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL23920659 | 0.75 | SIRT2 (0.51) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL8404027 | 0.74 | TSHR (0.58) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL14010662 | 0.74 | TSHR (0.58) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL736439 | 0.74 | TSHR (0.61) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL29389351 | 0.74 | TSHR (0.61) | TSHRNPSR1RXFP1POLBMAPK1 | |
| SCHEMBL17110689 | 0.72 | TSHR (0.59) | TSHRNPSR1RXFP1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112654-B2 | Ligand for vascular endothelial growth factor receptor | SUPRATEK PHARMA INC. (CA) | 2006-09-26 | — | — | US | disclosed |
| US-20040266694-A1 | Ligand for vascular endothelial growth factor receptor | SUPRATEK PHARMA INC. (CA) | 2004-12-30 | — | — | US | disclosed |
| US-6733755-B2 | PEPTIDE LIGAND OR DERIVATIVES THEREOF THAT ARE CAPABLE OF INHIBITING ANGIOGENESIS INDUCED BY VEGF. | SUPRATEK PHARMA, INC. (CA) | 2004-05-11 | — | — | US | disclosed |
| US-6696274-B2 | POLYPEPTIDES CAPABLE OF CROSSING THE SMALL INTESTINE OR BLOOD BRAIN BARRIER; BIOAVAILABILITY | SUPRATEK PHARMA, INC. (CA) | 2004-02-24 | — | — | US | disclosed |
| EP-1385873-A2 | A LIGAND FOR ENHANCING ORAL AND CNS DELIVERY OF BIOLOGICAL AGENTS | SUPRATEK PHARMA, INC. (CA) | 2004-02-04 | — | — | EP | disclosed |
| US-20020137684-A1 | Ligand for enhancing oral and CNS delivery of biological agents | SUPRATEK PHARMA, INC. (CA) | 2002-09-26 | — | — | US | disclosed |
| WO-2001090139-A2 | A LIGAND FOR ENHANCING ORAL AND CNS DELIVERY OF BIOLOGICAL AGENTS | SUPRATEK PHARMA INC. (US) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266694-A1 | Ligand for vascular endothelial growth factor receptor | FLT1, KDR, FLT4 | TSHR 562/4885NPSR1 221/4885RXFP1 129/4885 |
| US-20020137684-A1 | Ligand for enhancing oral and CNS delivery of biological agents | VIP, IGFBP6, GMFG | TSHR 579/4885NPSR1 189/4885RXFP1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.