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IGFBP6

Insulin-like growth factor-binding protein 6 · P24592 · IGFBP6 on Sugi Atlas →

48 patent compounds predicted against IGFBP6, 34 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL10923514 SCHEMBL10923514 0.47 2/20
SCHEMBL29360098 SCHEMBL29360098 0.47 2/20
SCHEMBL21979549 SCHEMBL21979549 0.46 2/20
SCHEMBL30514356 SCHEMBL30514356 0.46 2/20
SCHEMBL5825926 SCHEMBL5825926 0.44 2/20
SCHEMBL29997546 SCHEMBL29997546 0.44 2/20
SCHEMBL29752092 SCHEMBL29752092 0.40 2/20
SCHEMBL22475758 SCHEMBL22475758 0.35 2/20
SCHEMBL29857355 SCHEMBL29857355 0.35 2/20
SCHEMBL6014808 SCHEMBL6014808 1.00 1/20
SCHEMBL29930436 SCHEMBL29930436 1.00 1/20
Water Water (SCHEMBL31319504) 0.97 1/20
SCHEMBL1758192 SCHEMBL1758192 0.50 1/20
SCHEMBL9217699 SCHEMBL9217699 0.46 1/20
SCHEMBL724972 SCHEMBL724972 0.45 1/20
SCHEMBL11374392 SCHEMBL11374392 0.45 1/20
SCHEMBL21935558 SCHEMBL21935558 0.45 1/20
Benzoic Acid Benzoic Acid (SCHEMBL27538220) 0.44 1/20
SCHEMBL8834235 SCHEMBL8834235 0.44 1/20
SCHEMBL19003399 SCHEMBL19003399 0.44 1/20

Clinical trials — most relevant to IGFBP6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients PHASE4COMPLETED
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis PHASE4COMPLETED
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer PHASE4WITHDRAWN
Efficacy of Oral Metformin vs Oral Doxycycline in Treating Acne Vulgaris PHASE4COMPLETED
Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer PHASE2COMPLETED
Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus PHASE2COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
A Prevention Trial in Subjects at High Risk for Breast Cancer PHASE2COMPLETED
Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy PHASE1/PHASE2COMPLETED
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate PHASE1COMPLETED
Estradiol-Receptor Blockade in Older Men and Women PHASE1COMPLETED
Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors nanCOMPLETED
Impact of Exercise on Body Composition in Premature Infants nanWITHDRAWN
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
Metabolic and Hormonal Effects of 5:2 Intermittent Fasting nanCOMPLETED
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events nanCOMPLETED
Follow-up to Adult Height of a Cohort of Subjects Born Small for the Gestational Age and Treated With Growth Hormone nanCOMPLETED
Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation nanUNKNOWN
Patient Fitness and Body Composition During Hematopoietic Stem Cell Transplantation nanACTIVE_NOT_RECRUITING
Effects of Growth Hormone in Chronically Ill Children nanWITHDRAWN
Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt nanNOT_YET_RECRUITING
Using IGF-1 for Nutritional Monitoring nanCOMPLETED
EXploring Inflammation and Social deTerminants Study in Breast Cancer Patients nanRECRUITING
Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer nanCOMPLETED
Metabolic and Inflammatory Responses to Hemodialysis and the Effect of a Meal nanCOMPLETED
Weight Reduction Intervention for Breast Cancer Survivors nanCOMPLETED
Effects of Standardized Meals on the Metabolic, Hormonal and Inflammatory Responses in Human nanCOMPLETED
Adipocytokines in Endometrial Cancer nanCOMPLETED
To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in the UK nanCOMPLETED
DianaWeb: Before and After Study Online Based Participatory Research on Breast Cancer Women nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a IGFBP6 binder may also engage these)

ProteinNameSimilarity
Q05718 — 1.000 Q05718 →
P47880 — 0.996 P47880 →
P35572 — 0.996 P35572 →
A4IIA2 — 0.986 A4IIA2 →
Q5XHC5 — 0.985 Q5XHC5 →
P24853 — 0.984 P24853 →
Q29400 — 0.982 Q29400 →
P47877 — 0.981 P47877 →
IGFBP2 Insulin-like growth factor-binding protein 2 0.980 landscape →
P12843 — 0.979 P12843 →
Q6Q484 — 0.979 Q6Q484 →
Q75ZP3 — 0.978 Q75ZP3 →
P21743 — 0.978 P21743 →
P49705 — 0.977 P49705 →
P47876 — 0.976 P47876 →
A5A8Y8 — 0.976 A5A8Y8 →
Q6GUQ1 — 0.975 Q6GUQ1 →
P47878 — 0.974 P47878 →
IGFBP1 Insulin-like growth factor-binding protein 1 0.973 landscape →
IGFBP3 Insulin-like growth factor-binding protein 3 0.973 landscape →
P13384 — 0.973 P13384 →
Q9NPY3 — 0.972 Q9NPY3 →
O75074 — 0.972 O75074 →
P24787 — 0.972 P24787 →
P24591 — 0.972 P24591 →
P20959 — 0.971 P20959 →
Q4G0M1 — 0.970 Q4G0M1 →
Q8K4G1 — 0.970 Q8K4G1 →
Q8K1E3 — 0.970 Q8K1E3 →
Q99944 — 0.970 Q99944 →