Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341880 | 0.96 | TSHR (0.58) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL20305199 | 0.92 | TSHR (0.54) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL28364886 | 0.92 | TSHR (0.54) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL58823 | 0.86 | TSHR (0.58) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL1991359 | 0.85 | TSHR (0.78) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL57600 | 0.85 | TSHR (0.56) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL1890425 | 0.84 | TSHR (0.61) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL2167093 | 0.83 | L3MBTL1 (0.54) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL2167509 | 0.83 | L3MBTL1 (0.54) | TSHRNAAACA1CA2CA7 | |
| SCHEMBL2167399 | 0.83 | L3MBTL1 (0.54) | TSHRNAAACA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567300-A | Synthesis method of gamma-amino alcohol containing continuous chiral center | 江苏大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117164492-A | Organic semiconductor g-C 3 N 4 Method for catalytic synthesis of (E) -vinyl selenone compound | 化学与精细化工广东省实验室 | 2023-12-05 | — | — | CN | claimed |
| CN-112661764-B | Tetrahydrofuran indole compound and preparation method and application thereof | 温州大学新材料与产业技术研究院 | 2022-10-28 | — | — | CN | claimed |
| CN-113004293-A | Tetrahydrofuran [2,3-b ] indoline compound and preparation method and application thereof | 温州大学新材料与产业技术研究院 | 2021-06-22 | — | — | CN | claimed |
| CN-112661764-A | Tetrahydrofuran indole compound and preparation method and application thereof | 温州大学新材料与产业技术研究院 | 2021-04-16 | — | — | CN | claimed |
| CN-107417615-B | Novel preparation method of chiral quinolinone derivative promoted by visible light | 华中师范大学 | 2019-12-13 | — | — | CN | claimed |
| EP-3154961-B1 | QUINAZOLINONE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2019-10-09 | — | — | EP | claimed |
| CN-110256757-A | A kind of quaternary alkylphosphonium salt composite antibacterial EVA shoe cushion material and preparation method thereof | 广州大学 | 2019-09-20 | — | — | CN | claimed |
| CN-110003042-A | α, α -difluoroallyl aromatic hydrocarbon compound and preparation method thereof | 南京工业大学 | 2019-07-12 | — | — | CN | claimed |
| US-10308639-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-06-04 | — | — | US | claimed |
| WO-1998030551-A1 | MACROCYCLIC INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFα SECRETION | ABBOTT LABORATORIES (US) | 1998-07-16 | — | — | WO | claimed |
| CN-1166825-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARM (GB) | 1997-12-03 | — | — | CN | claimed |
| EP-0793641-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-09-10 | — | — | EP | claimed |
| WO-1997019053-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-05-29 | — | — | WO | claimed |
| WO-1997003783-A9 | METALLOPROTEINASE INHIBITORS | — | 1997-04-03 | — | — | WO | claimed |
| WO-1997003783-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-02-06 | — | — | WO | claimed |
| WO-1996016931-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-06-06 | — | — | WO | claimed |
| US-4960873-A | 3-pyridylisothiazoleazo compounds useful as disperse dyes | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |
| US-4016152-A | SUITABLE FOR DYEING POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | claimed |
| US-3933800-A | O-SUBSTITUTED OXIMES, MICROBIOCIDES | GRUPPO LEPETIT S.P.A. (IT) | 1976-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308639-B2 | Phosphatidylinositol 3-kinase inhibitors | PIK3CA, AKT3, AKT2 | TSHR 1850/4885NAAA 3176/4885CA1 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.