Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 4/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57600 | 0.94 | TSHR (0.56) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL2167399 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL8501290 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL8497842 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL8497248 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL2167093 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL2167509 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL8498777 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL8500321 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 | |
| SCHEMBL59225 | 0.92 | L3MBTL1 (0.54) | TSHRTDP1L3MBTL1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384079-B | Chiral N-alkyl indole compound and preparation method and application thereof | 云南大学 | 2024-05-24 | — | — | CN | claimed |
| CN-117384079-A | Chiral N-alkyl indole compound and preparation method and application thereof | 云南大学 | 2024-01-12 | — | — | CN | claimed |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | claimed |
| EP-4153573-A1 | HERBICIDAL CINNOLINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2023-03-29 | — | — | EP | claimed |
| CN-115697975-A | Herbicidal cinnoline derivatives | 先正达农作物保护股份公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114341110-A | Aminothiol ester compound and use thereof | 高级生物设计公司 | 2022-04-12 | — | — | CN | claimed |
| WO-2021233787-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-11-25 | — | — | WO | claimed |
| EP-3833657-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | Advanced Biodesign (FR) | 2021-06-16 | — | — | EP | claimed |
| WO-2021019071-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | ADVANCED BIODESIGN (FR) | 2021-02-04 | — | — | WO | claimed |
| US-6838472-B2 | For treating or preventing emphysema, cancer and dermatological disorders | SYNTEX (U.S.A.) LLC (US) | 2005-01-04 | — | — | US | claimed |
| WO-1998030541-A1 | C-TERMINAL KETONE HYDROXAMIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFA SECRETION | ABBOTT LABORATORIES (US) | 1998-07-16 | — | — | WO | claimed |
| WO-1998030551-A1 | MACROCYCLIC INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFα SECRETION | ABBOTT LABORATORIES (US) | 1998-07-16 | — | — | WO | claimed |
| US-5763621-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | claimed |
| EP-0821668-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| EP-0821666-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| EP-0777646-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-06-11 | — | — | EP | claimed |
| WO-1996033165-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | claimed |
| WO-1996033161-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | claimed |
| WO-1996006074-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-02-29 | — | — | WO | claimed |
| US-3933800-A | O-SUBSTITUTED OXIMES, MICROBIOCIDES | GRUPPO LEPETIT S.P.A. (IT) | 1976-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | DDT, CYP1B1, DERL1 | TSHR 3874/4885TDP1 1561/4885L3MBTL1 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.