SCHEMBL583592

SCHEMBL583592

CNC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.63
ALPI P09923 1/20 0.63
PKM P14618 1/20 0.63
PTGS1 P23219 1/20 0.63
XIAP P98170 1/20 0.63
SLC15A1 P46059 1/20 0.59
CTSC P53634 2/20 0.58
LTA4H P09960 1/20 0.56
ANPEP P15144 1/20 0.51
RNPEP Q9H4A4 1/20 0.51
DNPEP Q9ULA0 1/20 0.51
BACE1 P56817 2/20 0.50
CTRB1 P17538 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989802 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL7648961 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL1262434 0.98 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL6164795 0.98 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL6164804 0.98 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL7268667 0.92 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL6967778 0.92 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3704073 0.90 CTSC (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3704071 0.90 CTSC (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL20669159 0.87 MMP1 (0.61) CTSCMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001684-B1 TETRAPEPTIDES, METHODS FOR THEIR PREPARATION AND THEIR USE IN ANALGESIC COMPOSITIONS ELI LILLY AND COMPANY (US) 1981-09-02 EP claimed
EP-0001684-A2 Tetrapeptides, methods for their preparation and their use in analgesic compositions ELI LILLY AND COMPANY (US) 1979-05-02 EP claimed
JP-63123398-A None JP disclosed
JP-63160599-A None JP disclosed
JP-57186495-A None JP disclosed
EP-4405330-A1 SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS Artizan Biosciences, Inc. (US) 2024-07-31 EP disclosed
WO-2024147125-A1 CYCLOBUTYL-SUBSTITUTED PHENOXY-DIOXETANES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-07-11 WO disclosed
CN-111479819-B Method for preparing peptide and method for treating alkali 中外制药株式会社 2024-06-14 CN disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
CN-116723854-A Tumor vaccination method 门德斯有限公司 2023-09-08 CN disclosed
US-20230242586-A1 RAS INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed
EP-0273689-A2 Derivatives of N-(2-alkyl-3-mercapto-glutaryl) alpha-amino acids and their use as collagenase inhibitors BEECHAM GROUP PLC (GB) 1988-07-06 EP disclosed
JP-S63160599-A PRODUCTION OF L-ALPHA-METHYLPHENYLALANINES MITSUBISHI GAS CHEM CO INC 1988-07-04 JP disclosed
JP-S63123398-A PRODUCTION OF L-ALPHA-METHYLPHENYLALANINES MITSUBISHI GAS CHEM CO INC 1988-05-27 JP disclosed
US-4704464-A CHELATE COMPOUNDS ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK (DE) 1987-11-03 US disclosed
EP-0193083-A1 Anti-tumoral(1-arylmethyl-ethylene diamine)-platinum(II)-complexes ASTA Pharma AG (DE) 1986-09-03 EP disclosed
EP-0019411-B1 1-PHENYL-2-AMINOETHANOL DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-12-22 EP disclosed
JP-S57186495-A PREPARATION OF L-ALPHA-METHYLPHENYLALANINE UBE IND LTD 1982-11-16 JP disclosed
EP-0001684-B1 TETRAPEPTIDES, METHODS FOR THEIR PREPARATION AND THEIR USE IN ANALGESIC COMPOSITIONS ELI LILLY AND COMPANY (US) 1981-09-02 EP disclosed
EP-0001684-A2 Tetrapeptides, methods for their preparation and their use in analgesic compositions ELI LILLY AND COMPANY (US) 1979-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242586-A1 RAS INHIBITORS AND USES THEREOF KRAS, NRAS, HRAS SLC7A5 3357/4885ALPI 1256/4885PKM 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.