Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 16/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835835 | 0.85 | TBXA2R (0.60) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5837002 | 0.83 | TBXA2R (0.71) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5772444 | 0.82 | TBXA2R (0.70) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5836698 | 0.81 | TBXA2R (0.57) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5834967 | 0.72 | TBXA2R (0.38) | TBXA2R | |
| SCHEMBL5835634 | 0.72 | TBXA2R (0.56) | TBXA2RPTGDR | |
| SCHEMBL5835468 | 0.69 | TBXA2R (0.35) | TBXA2R | |
| SCHEMBL5836349 | 0.68 | TBXA2R (0.78) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5773893 | 0.65 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5776058 | 0.65 | TBXA2R (0.73) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144913-B2 | Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists | MERCK FROSST CANADA & CO. (CA) | 2006-12-05 | — | — | US | disclosed |