Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752826 | 0.82 | HTT (0.66) | HTTL3MBTL1USP2ALDH1A1HPGD | |
| SCHEMBL916860 | 0.81 | FOLH1 (0.53) | HTTUSP2FOLH1ALDH1A1HPGD | |
| SCHEMBL10824828 | 0.77 | HTT (0.65) | HTTL3MBTL1USP2ALDH1A1HPGD | |
| Butane SCHEMBL11004584 | 0.75 | TSHR (0.47) | HTTUSP2FOLH1ALDH1A1HPGD | |
| SCHEMBL69352 | 0.73 | TSHR (0.68) | HTTFOLH1ALDH1A1HPGDALOX15 | |
| SCHEMBL70392 | 0.73 | FOLH1 (0.76) | HTTFOLH1ALDH1A1HPGDALOX15 | |
| SCHEMBL30365583 | 0.73 | FOLH1 (0.76) | HTTFOLH1ALDH1A1HPGDALOX15 | |
| SCHEMBL10431512 | 0.73 | HTT (0.61) | HTTL3MBTL1USP2ALDH1A1HPGD | |
| SCHEMBL29119914 | 0.73 | HTT (0.56) | HTTL3MBTL1USP2ALDH1A1HPGD | |
| SCHEMBL25936994 | 0.72 | HTT (0.55) | HTTL3MBTL1USP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122703-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-17 | — | — | US | disclosed |
| US-20030199084-A1 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199084-A1 | Chemoselective ligation | PTMS, QPCT, DNPEP | HTT 4033/4885L3MBTL1 616/4885USP2 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.