SCHEMBL5836828

SCHEMBL5836828

CC1=Cc2c(C)cc(C)cc2C1[Si](C)(C)C1C(C)=Cc2c(C)cc(C)cc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UGT2B17 O75795 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045461 0.86 MEN1 (0.31)
SCHEMBL1452163 0.86
SCHEMBL2046390 0.85
SCHEMBL1451562 0.84
SCHEMBL1452549 0.74 TERT (0.31)
SCHEMBL1453207 0.74 CRHR1 (0.33)
SCHEMBL1454519 0.73 HTR2C (0.31)
SCHEMBL9421537 0.72 UGT2B17 (0.32) UGT2B17
SCHEMBL5860056 0.72 UGT2B17 (0.32) UGT2B17
SCHEMBL4628523 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770587-B1 Process for the production of an indene compound and its use for the production of a metallocene catalyst BASELL POLYOLEFINE GMBH (DE) 2006-03-22 EP disclosed
US-6984743-B1 Method for producing metallocenes BASELL POLYOLEFINE GMBH (DE) 2006-01-10 US disclosed
US-6620953-B1 Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts BASSELL POLYOLEFINE GMBH (DE) 2003-09-16 US disclosed
EP-1133504-B1 METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2003-03-12 EP disclosed
EP-1015463-B1 METHOD FOR PRODUCING METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2002-12-11 EP disclosed
EP-0545304-B1 Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts BASELL POLYOLEFINE GMBH (DE) 2002-06-19 EP disclosed
US-6051522-A Catalyst which can be used for the preparation of olefins during polymerization TARGOR GMBH (DE) 2000-04-18 US disclosed
US-5929264-A Process for the preparation of substituted indenes and their use as ligand systems for metallocene catalysts TARGOR GMBH (DE) 1999-07-27 US disclosed
EP-0617044-B1 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI CHEMICALS INC (JP) 1999-01-20 EP disclosed
US-5852142-A Process for the preparation of an olefin polymer TARGOR GMBH (DE) 1998-12-22 US disclosed
US-5840948-A Process for the preparation of substituted indenes and their use as ligand systems for metallocene catalysts TARGOR GMBH (DE) 1998-11-24 US disclosed
EP-0545303-B1 Process for preparing high molecular weight polyolefins HOECHST AG (DE) 1997-10-01 EP disclosed
EP-0770587-A2 Process for the production of an indene compound and its use for the production of a metallocene catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-02 EP disclosed
US-5374752-A Catalyst system containing metallocene HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-20 US disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed
EP-0545303-A1 Process for preparing high molecular weight polyolefins HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed
EP-0545304-A1 Process for the preparation of substituted indenes and their use as ligands for metallocene catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed