Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188498 | 1.00 | GRM5 (0.54) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL28911964 | 0.86 | GAA (0.51) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL1840355 | 0.83 | GAA (0.60) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL1839289 | 0.80 | GAA (0.59) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL31231772 | 0.80 | GAA (0.59) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL30043736 | 0.79 | GRM5 (0.57) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL30044683 | 0.79 | ANO1 (0.54) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL29660974 | 0.79 | ANO1 (0.50) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL29836003 | 0.79 | GRM5 (0.53) | GRM5GAAMAPTFPR2LMNA | |
| SCHEMBL10152388 | 0.78 | GRM5 (0.79) | GRM5GAAMAPTFPR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049537-B1 | CATALYTIC COMPOSITIONS AND METHODS FOR ASYMMETRIC ALLYLIC ALKYLATION | UNIV LELAND STANFORD JUNIOR (US) | 2003-08-06 | — | — | EP | claimed |
| EP-1049537-A2 | CATALYTIC COMPOSITIONS AND METHODS FOR ASYMMETRIC ALLYLIC ALKYLATION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-11-08 | — | — | EP | claimed |
| WO-1999032225-A9 | CATALYTIC COMPOSITION BASED ON CHIRAL LIGANDS WITH MOLYBDENUM, TUNGSTEN OR CHROMIUM AND METHOD FOR ASYMMETRIC ALKYLATION OF ALLYLIC SUBSTRATES | UNIV LELAND STANFORD JUNIOR (US) | 1999-09-30 | — | — | WO | claimed |
| WO-1999032225-A2 | CATALYTIC COMPOSITION BASED ON CHIRAL LIGANDS WITH MOLYBDENUM, TUNGSTEN OR CHROMIUM AND METHOD FOR ASYMMETRIC ALKYLATION OF ALLYLIC SUBSTRATES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1999-07-01 | — | — | WO | claimed |
| US-7005521-B1 | Catalytic compositions and methods for asymmetric allylic alkylation | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2006-02-28 | — | — | US | disclosed |
| EP-1049537-B1 | CATALYTIC COMPOSITIONS AND METHODS FOR ASYMMETRIC ALLYLIC ALKYLATION | UNIV LELAND STANFORD JUNIOR (US) | 2003-08-06 | — | — | EP | disclosed |
| US-6130349-A | USING COMPLEX OF MOLYBDENUM, TUNGSTEN OR CHROMIUM WITH 1,1*-BINAPHTHYL SYSTEM CONTAINING HETEROCYCLIC NITROGEN GROUP; ENANTIO- AND REGIOSELECTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-10-10 | — | — | US | disclosed |