Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GRM5 | P41594 | 4/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188498 | 0.86 | GRM5 (0.54) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL5836837 | 0.86 | GRM5 (0.54) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL1840355 | 0.82 | GAA (0.60) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL1839289 | 0.79 | GAA (0.59) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL31231772 | 0.79 | GAA (0.59) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL30043736 | 0.78 | GRM5 (0.57) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL30044683 | 0.78 | ANO1 (0.54) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL29660974 | 0.78 | ANO1 (0.50) | GAAMAPTGRM5FPR2LMNA | |
| SCHEMBL14074318 | 0.78 | CES2 (0.48) | GAAMAPTGRM5LMNAHDAC3 | |
| SCHEMBL29836003 | 0.78 | GRM5 (0.53) | GAAMAPTGRM5FPR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739345-A | PIM kinase inhibitor compositions, methods and uses thereof | 斯奈普生物公司 | 2021-04-30 | — | — | CN | disclosed |