Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038278 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| SCHEMBL7037711 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| SCHEMBL3965890 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| SCHEMBL8469174 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1CYP2A6CYP1A2CYP2C19 | |
| SCHEMBL9249191 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| SCHEMBL8673527 | 0.72 | CYP2A6 (0.42) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL7734464 | 0.71 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL6064180 | 0.71 | CYP2A6 (0.41) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL4063684 | 0.71 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL3092658 | 0.71 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP2A6MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049377-B1 | 1,3-diethers and components and catalysts for the polymerization of olefins, containing said diethers | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2006-05-23 | — | — | US | disclosed |
| EP-0728770-B1 | Process for the preparation of solid catalyst components for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-07-14 | — | — | EP | disclosed |