Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837005 | 0.88 | PPARG (0.31) | — | |
| SCHEMBL5836758 | 0.80 | AKR1C3 (0.32) | — | |
| SCHEMBL5836290 | 0.79 | PDCD1 (0.31) | — | |
| SCHEMBL7038278 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1CYP2A6CYP1A2CYP2C19 | |
| SCHEMBL7037711 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1CYP2A6CYP1A2CYP2C19 | |
| SCHEMBL6554746 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1CYP2A6CYP1A2CYP2C19 | |
| SCHEMBL6235805 | 0.74 | HTR2A (0.33) | KDM4E | |
| SCHEMBL5836859 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1CYP2A6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL4063684 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL3965890 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932669-A | HOMO OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITIONAL METAL COMPOUND AS A METALLOCENE CATALYST AND ALUMINOXANE AS COCATALYST | TARGOR GMBH (DE) | 1999-08-03 | — | — | US | disclosed |
| US-5830821-A | POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0549900-B1 | Metallocenes containing benzocondensed indenyl derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| US-5455366-A | Olefin polymerization catalysts | HOECHST AG (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0549900-A1 | Metallocenes containing benzocondensed indenyl derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-07 | — | — | EP | disclosed |