Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277608 | 0.94 | P2RX7 (0.35) | P2RX7CNR2CNR1 | |
| SCHEMBL5957066 | 0.92 | P2RX7 (0.45) | P2RX7CNR2CNR1MEN1KMT2A | |
| SCHEMBL5957156 | 0.92 | P2RX7 (0.38) | P2RX7CNR2CNR1TAAR1 | |
| SCHEMBL5838688 | 0.90 | P2RX7 (0.39) | P2RX7CNR2CNR1KMT2ATAAR1 | |
| SCHEMBL5837096 | 0.89 | P2RX7 (0.39) | P2RX7CNR2CNR1 | |
| SCHEMBL5838779 | 0.87 | P2RX7 (0.38) | P2RX7CNR2CNR1 | |
| SCHEMBL5838229 | 0.87 | KMT2A (0.38) | P2RX7CNR2KMT2ATAAR1 | |
| SCHEMBL5838492 | 0.87 | ALDH1A1 (0.37) | P2RX7CNR2CNR1MEN1KMT2A | |
| SCHEMBL5838488 | 0.86 | P2RX7 (0.39) | P2RX7CNR2CNR1MEN1KMT2A | |
| SCHEMBL5838879 | 0.86 | P2RX7 (0.36) | P2RX7CNR2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060217430-A1 | Benzamide inhibitors of the P2X7 receptor | DOMBROSKI MARK A | 2006-09-28 | — | — | US | disclosed |
| US-7071223-B1 | Benzamide inhibitors of the P2X7 receptor | PFIZER, INC. (US) | 2006-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217430-A1 | Benzamide inhibitors of the P2X7 receptor | IL1R1, P2RY1, P2RX1 | P2RX7 7/4885CNR2 117/4885CNR1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.