Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043313 | 0.89 | PNMT (0.49) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL8971039 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL27835838 | 0.83 | PNMT (0.47) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7607951 | 0.83 | PNMT (0.39) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL62724 | 0.83 | PNMT (0.39) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL6675362 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL6675358 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL8861800 | 0.81 | PNMT (0.54) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL27942181 | 0.81 | PNMT (0.49) | PNMTNPC1RAB9AHTR2BHTR7 | |
| SCHEMBL7877087 | 0.81 | PNMT (0.49) | PNMTNPC1RAB9AHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984743-B1 | Method for producing metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2006-01-10 | — | — | US | disclosed |
| EP-1015463-B1 | METHOD FOR PRODUCING METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2002-12-11 | — | — | EP | disclosed |
| EP-0604908-A2 | Metallocene compounds having ligands of fluorenylic type | Montell Technology Company bv (NL) | 1994-07-06 | — | — | EP | disclosed |