SCHEMBL8971039

SCHEMBL8971039

CC(Cl)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
HTR7 P34969 1/20 0.38
HTR2B P41595 1/20 0.38
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
PGR P06401 1/20 0.36
MAOA P21397 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
MAP3K9 P80192 1/20 0.35
MAP3K11 Q16584 1/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2043313 0.85 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5837265 0.85 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27835838 0.80 PNMT (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8861800 0.78 PNMT (0.54) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27942181 0.78 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7877087 0.78 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL994679 0.78 PNMT (0.40) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL21758196 0.77 NPC1 (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30103334 0.76 PNMT (0.63) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL524602 0.76 PNMT (0.63) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5492974-A Process for preparing polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492978-A Process for preparing catalyst system PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492973-A Polymer bound ligands PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492985-A Polymerization processes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492975-A Polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
EP-0690076-A1 Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-01-03 EP disclosed
US-5473020-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-12-05 US disclosed