SCHEMBL5837307

SCHEMBL5837307

O=C(OC(F)(F)F)[C@@H]1[C@@H](C(=O)O)[C@H]2C=C[C@@H]1C2

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.51
ALDH1A1 P00352 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TDP1 Q9NUW8 2/20 0.45
APEX1 P27695 1/20 0.45
LMNA P02545 1/20 0.44
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837310 1.00 POLB (0.51) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL5837776 0.93 ALDH1A1 (0.41) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL5837416 0.82 POLB (0.51) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL3150000 0.82 POLB (0.51) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL4665372 0.79 POLB (0.59) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL572756 0.79 POLB (0.59) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL27495 0.79 POLB (0.59) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL3787744 0.79 POLB (0.59) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL3777075 0.79 POLB (0.59) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL3590114 0.78 ALDH1A1 (0.59) POLBALDH1A1SMN1; SMN2TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed