SCHEMBL5837332

SCHEMBL5837332

CC1C2C=CC(C2)C1(CC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
HSD11B1 P28845 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4810930 0.67 TDP1 (0.32) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL7699416 0.66 ALDH1A1 (0.36) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL4880104 0.65 KDM4E (0.35) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL14301947 0.65 TDP1 (0.38) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL18911754 0.64 KDM4E (0.32) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL13483357 0.63 KDM4E (0.40) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL3196385 0.63 KDM4E (0.40) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL3196381 0.63 KDM4E (0.40) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL8618809 0.62 TDP1 (0.48) KDM4EKMT2AALDH1A1TDP1MEN1
SCHEMBL4885151 0.62 HSD11B1 (0.33) KDM4EALDH1A1POLBHSD11B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100386357-C Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORP (JP) 2008-05-07 CN disclosed
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
CN-1659205-A Norbornene-based ring-opening polymer, hydrogenation product of norbornene-based ring-opening polymer, and method for producing same ZEON CORP (JP) 2005-08-24 CN disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed