SCHEMBL5838113

SCHEMBL5838113

CC(C)(C)COC(=O)C(=CC=C(c1ccccc1)c1ccccc1)C(=O)OCC(C)(C)C.CCCCC(CC)COc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
LMNA P02545 4/20 0.41
ALDH1A1 P00352 5/20 0.40
MAPK1 P28482 3/20 0.40
CYP1A2 P05177 1/20 0.40
PGR P06401 1/20 0.40
CYP2D6 P10635 1/20 0.40
SLC6A2 P23975 1/20 0.40
PDE4A P27815 1/20 0.40
CYP2C19 P33261 1/20 0.40
HRH1 P35367 1/20 0.40
HTT P42858 1/20 0.40
SLC6A3 Q01959 1/20 0.40
PDE4D Q08499 1/20 0.40
CYP3A4 P08684 2/20 0.39
CA2 P00918 1/20 0.39
TSHR P16473 1/20 0.38
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431903 0.84 HPGD (0.58) HPGDLMNAALDH1A1MAPK1CYP1A2
SCHEMBL534051 0.84 HPGD (0.58) HPGDLMNAALDH1A1MAPK1CYP1A2
SCHEMBL7162160 0.78 ALDH1A1 (0.60) LMNAALDH1A1MAPK1CYP3A4CA2
SCHEMBL28464275 0.77 HPGD (0.64) HPGDLMNAALDH1A1MAPK1CYP1A2
SCHEMBL10613842 0.76 HPGD (0.51) HPGDLMNAALDH1A1MAPK1CYP1A2
SCHEMBL10613829 0.76 HPGD (0.51) HPGDLMNAALDH1A1MAPK1CYP1A2
SCHEMBL11436864 0.73 HPGD (0.46) HPGDLMNAALDH1A1MAPK1CYP1A2
SCHEMBL4653551 0.73 LMNA (0.51) LMNAALDH1A1MAPK1CYP3A4CA2
SCHEMBL4653975 0.72 LMNA (0.50) LMNAALDH1A1MAPK1CYP3A4CA2
SCHEMBL2482330 0.71 HPGD (0.68) HPGDLMNAALDH1A1MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060076542-A1 UV absorber mixture with affinity for textile fiber BASF AKTIENGESELLSCHAFT (DE) 2006-04-13 US disclosed
US-7011772-B2 UV absorbing mixture with textile fiber affinity BASF AKTIENGESELLSCHAFT (DE) 2006-03-14 US disclosed
US-20030127633-A1 Uv absorbing mixture with textile fiber affinity BASF AKTIENGESELLSCHAFT (DE) 2003-07-10 US disclosed