SCHEMBL5838176

SCHEMBL5838176

CC(C)(c1ccccn1)C(N[Si](C)(C)C)N[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CHRM2 P08172 1/20 0.35
HRH3 Q9Y5N1 1/20 0.33
ALDH1A1 P00352 5/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 3/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALOX15 P16050 1/20 0.33
AGTR1 P30556 1/20 0.32
AHR P35869 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
POLB P06746 1/20 0.31
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31
METAP1 P53582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5840135 0.83 SMN1; SMN2 (0.40) SMN1; SMN2L3MBTL1CHRM2HRH3ALDH1A1
SCHEMBL20809866 0.75 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1CHRM2HRH3ALDH1A1
SCHEMBL5839167 0.73 SMN1; SMN2 (0.38) SMN1; SMN2L3MBTL1ALDH1A1KDM4ELMNA
SCHEMBL5839663 0.73 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1CHRM2ALDH1A1TDP1
SCHEMBL28341098 0.72 L3MBTL1 (0.47) SMN1; SMN2L3MBTL1CHRM2ALDH1A1TDP1
SCHEMBL5840008 0.71 SLC40A1 (0.39) SMN1; SMN2L3MBTL1LMNAHDAC6
SCHEMBL28883610 0.69 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2ALDH1A1TDP1
SCHEMBL29349628 0.69 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2ALDH1A1TDP1
SCHEMBL29080 0.69 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2ALDH1A1TDP1
SCHEMBL31645911 0.69 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6992034-B2 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2006-01-31 US disclosed
US-20050009690-A1 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATIONS, U.S.A. 2005-01-13 US disclosed