Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SCN1A | P35498 | 2/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30300553 | 0.86 | MEN1 (0.62) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL28707285 | 0.85 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL10356574 | 0.83 | KDR (0.48) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL1232491 | 0.81 | MAPT (0.58) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL28911206 | 0.80 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL11775586 | 0.80 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL10567645 | 0.80 | MAPT (0.66) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL5892506 | 0.80 | KMT2A (0.65) | MEN1KMT2ACYP1A2CYP2C9NFKB1 | |
| SCHEMBL7138056 | 0.79 | KMT2A (0.50) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL8398430 | 0.79 | CA1 (0.43) | MEN1KMT2ACYP1A2CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697639-B2 | Quaternary ammonium salt compound, preparation method therefor and use thereof | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2023-07-11 | — | — | US | disclosed |
| US-20210107872-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2021-04-15 | — | — | US | disclosed |
| EP-3750870-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | West China Hospital, Sichuan University (CN) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154288-A1 | CATIONIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学华西医院 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019154287-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学华西医院 | 2019-08-15 | — | — | WO | disclosed |
| US-7033765-B1 | Site-specific drug delivery | TORONTO RESEARCH CHEMICALS, INC. (CA) | 2006-04-25 | — | — | US | disclosed |
| US-20060009375-A1 | Site-specific drug delivery | TORONTO RESEARCH CHEMICALS, INC. (CA) | 2006-01-12 | — | — | US | disclosed |
| EP-0966304-B1 | SITE-SPECIFIC DRUG DELIVERY | DIME DAVID S (CA) | 2005-05-25 | — | — | EP | disclosed |
| EP-1140803-B1 | ((AMINOIMINOMETHYL) AMINO) ALKANECARBOXAMIDES AND THEIR APPLICATIONS IN THERAPY | MERCK PATENT GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6576791-B1 | Local anesthetic compounds and uses | THERAVANCE, INC. | 2003-06-10 | — | — | US | disclosed |
| US-6337423-B1 | BIND TO VOLTAGE-GATED SODIUM ION CHANNELS TO MODULATE ACTIVITY | ADVANCED MEDICINE, INC. | 2002-01-08 | — | — | US | disclosed |
| EP-1140803-A1 | ((AMINOIMINOMETHYL) AMINO) ALKANECARBOXAMIDES AND THEIR APPLICATIONS IN THERAPY | MERCK PATENT GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-1999064045-A9 | NOVEL THERAPEUTIC AGENTS FOR MEMBRANE TRANSPORTERS | ADVANCED MEDICINE INC (US) | 2001-07-05 | — | — | WO | disclosed |
| EP-1066245-A4 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | ADVANCED MEDICINE INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1066245-A1 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | Advanced Medicine, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-2000042001-A1 | ((AMINOIMINOMETHYL) AMINO) ALKANECARBOXAMIDES AND THEIR APPLICATIONS IN THERAPY | MERCK PATENT GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |
| EP-0966304-A1 | SITE-SPECIFIC DRUG DELIVERY | Dime, David S. (CA) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999051565-A9 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | ADVANCED MEDICINE INC (US) | 1999-12-02 | — | — | WO | disclosed |
| WO-1999051565-A1 | NOVEL LOCAL ANESTHETIC COMPOUNDS AND USES | ADVANCED MEDICINE, INC. (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1998036777-A1 | SITE-SPECIFIC DRUG DELIVERY | DIME DAVID S (CA) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697639-B2 | Quaternary ammonium salt compound, preparation method therefor and use thereof | SCN11A, SLC6A11, SCN8A | MEN1 2906/4885KMT2A 3172/4885CYP1A2 3171/4885 |
| US-20060009375-A1 | Site-specific drug delivery | ABCG2, ABCB1, DHFR | MEN1 3755/4885KMT2A 3341/4885CYP1A2 357/4885 |
| US-20210107872-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SCN11A, SLC6A11, SCN8A | MEN1 2906/4885KMT2A 3172/4885CYP1A2 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.