Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837976 | 0.87 | CXCR2 (0.33) | MAPT | |
| SCHEMBL5838078 | 0.83 | GRM6 (0.36) | MAPTGRM6 | |
| SCHEMBL5838338 | 0.79 | ALDH1A1 (0.32) | GRM6 | |
| SCHEMBL5838406 | 0.77 | GRM6 (0.40) | MAPTGRM6 | |
| SCHEMBL5837464 | 0.75 | ADORA1 (0.35) | MAPTGRM6 | |
| SCHEMBL5837610 | 0.74 | MAPT (0.33) | MAPTGRM6 | |
| SCHEMBL5838606 | 0.70 | ADORA1 (0.36) | MAPTGRM6 | |
| SCHEMBL5838694 | 0.70 | GRM6 (0.33) | MAPTGRM6 | |
| SCHEMBL6316939 | 0.70 | CXCR2 (0.39) | MAPT | |
| SCHEMBL7861195 | 0.70 | ADORA1 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115624-B1 | Method of inhibiting protein tyrosine phosphatase 1B and/or T-cell protein tyrosine phosphatase 4 and/or other PTPases with an Asp residue at position 48 | NOVO NORDISK A/S (DK) | 2006-10-03 | — | — | US | disclosed |
| US-7019026-B1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2006-03-28 | — | — | US | disclosed |
| EP-1214325-B1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK AS (DK) | 2005-11-09 | — | — | EP | disclosed |
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |