Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367675 | 0.86 | PTPN1 (0.53) | MAPTHTTTSHRMEN1KMT2A | |
| SCHEMBL4364688 | 0.86 | NPC1 (0.51) | MAPTHTTMEN1KMT2ARAB9A | |
| SCHEMBL4370663 | 0.85 | NPC1 (0.47) | MAPTHTTTSHRMEN1KMT2A | |
| SCHEMBL4364701 | 0.82 | KMT2A (0.51) | MAPTNOX1MEN1KMT2ARAB9A | |
| SCHEMBL5838476 | 0.79 | MAPT (0.72) | MAPTHTTMAPK1TSHRNOX1 | |
| SCHEMBL4366082 | 0.79 | NPC1 (0.56) | MAPTHTTKMT2ARAB9ANPC1 | |
| SCHEMBL4367832 | 0.78 | MEN1 (0.46) | MAPTMAPK1TSHRMEN1KMT2A | |
| SCHEMBL4363888 | 0.78 | RAB9A (0.63) | MAPTMAPK1TSHRMEN1KMT2A | |
| SCHEMBL4365796 | 0.77 | NPC1 (0.42) | HTTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4365410 | 0.75 | ALDH1A1 (0.46) | MAPTHTTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094807-B2 | Substituted aryl thioureas and related compounds; inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. (US) | 2006-08-22 | — | — | US | disclosed |