Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18949789 | 0.82 | MAOB (0.51) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5839687 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL28638554 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TDP1MRGPRX4MEN1KMT2A | |
| SCHEMBL5839209 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHTTPOLB | |
| Phthalic Acid SCHEMBL8740470 | 0.78 | TSHR (0.83) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5839145 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MRGPRX4KMT2AHTTTP53 | |
| SCHEMBL5838528 | 0.77 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5839828 | 0.77 | MRGPRX4 (0.55) | ALDH1A1TDP1MRGPRX4MEN1KMT2A | |
| SCHEMBL21545836 | 0.76 | KMT2A (0.59) | ALDH1A1TDP1MEN1KMT2AHTT | |
| SCHEMBL33663 | 0.76 | TSHR (1.00) | TSHRALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |