Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.55 |
| ▸ | FABP3 | P05413 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPD | P32754 | 2/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839484 | 0.82 | FABP3 (0.78) | MRGPRX4FABP3FABP4FABP5MEN1 | |
| SCHEMBL5839209 | 0.81 | ALDH1A1 (0.54) | MEN1MAPTKMT2AALDH1A1HTT | |
| SCHEMBL3834884 | 0.80 | HPSE (0.55) | MEN1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL5839970 | 0.79 | MRGPRX4 (0.67) | MRGPRX4FABP3FABP4FABP5KMT2A | |
| SCHEMBL5839687 | 0.78 | ALDH1A1 (0.50) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL10502048 | 0.78 | MAPT (0.50) | MRGPRX4MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10502108 | 0.77 | MEN1 (0.54) | MEN1MAPTKMT2AHTTCYP1A2 | |
| SCHEMBL5838506 | 0.77 | TSHR (0.59) | MRGPRX4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL15243653 | 0.76 | MRGPRX4 (0.53) | MRGPRX4MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL18949789 | 0.76 | MAOB (0.51) | MEN1MAPTKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |