Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838556 | 1.00 | MAPT (0.70) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL30141094 | 0.93 | PDE4A (0.63) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL30892448 | 0.93 | PDE4A (0.63) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL24983864 | 0.93 | PDE4A (0.63) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL29179321 | 0.93 | PDE4A (0.63) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL5433412 | 0.90 | ABCG2 (0.76) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL30384422 | 0.90 | ABCG2 (0.76) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL25192256 | 0.90 | ABCG2 (0.76) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL25193887 | 0.90 | ABCG2 (0.76) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL30383596 | 0.90 | ABCG2 (0.76) | MAPTKMT2ACYP3A4TP53ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122573-B2 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL (US) | 2006-10-17 | — | — | US | disclosed |
| US-7109236-B2 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1581512-A2 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | SRI INTERNATIONAL (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040192723-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL | 2004-09-30 | — | — | US | disclosed |
| WO-2004052873-A9 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | STANFORD RES INST INT (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004052873-A2 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | SRI INTERNATIONAL (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040110790-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192723-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | TEAD4, TEAD3, TEAD1 | MAPT 2442/4885KMT2A 2705/4885CYP3A4 121/4885 |
| US-20040110790-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | TEAD4, TEAD3, TEAD1 | MAPT 2442/4885KMT2A 2705/4885CYP3A4 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.