Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KDM5C | P41229 | 3/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12251401 | 0.90 | PHF8 (0.44) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL14576169 | 0.90 | PHF8 (0.42) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL17762997 | 0.89 | ECE1 (0.42) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL93812 | 0.88 | GAA (0.49) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL27665153 | 0.87 | KDM5A (0.53) | PHF8KDM4ELMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL93987 | 0.86 | GAA (0.48) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| Hydrochloric Acid SCHEMBL27665152 | 0.86 | KDM5A (0.51) | PHF8KDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL6810784 | 0.85 | PHF8 (0.60) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL17974599 | 0.85 | ECE1 (0.39) | PHF8KDM2AKDM7AECE1LMNA | |
| SCHEMBL30571376 | 0.84 | PHF8 (0.44) | PHF8KDM2AKDM4EKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020016451-A1 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | CAPROTEC BIOANALYTICS GMBH (DE) | 2002-02-07 | — | — | US | claimed |
| US-20020007048-A1 | Solution Phase Biopolymer Synthesis | CAPROTEC BIOANALYTICS GMBH (DE) | 2002-01-17 | — | — | US | claimed |
| EP-1073668-A2 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | Köster, Hubert (US) | 2001-02-07 | — | — | EP | claimed |
| WO-1999055718-A2 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | KOESTER HUBERT (US) | 1999-11-04 | — | — | WO | claimed |
| US-7094943-B2 | Solution phase biopolymer synthesis | Köster, Hubert (US) | 2006-08-22 | — | — | US | disclosed |
| US-7038103-B2 | Solution phase biopolymer synthesis | HUBERT KOSTER (CH) | 2006-05-02 | — | — | US | disclosed |
| US-20020016451-A1 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | CAPROTEC BIOANALYTICS GMBH (DE) | 2002-02-07 | — | — | US | disclosed |
| US-20020007048-A1 | Solution Phase Biopolymer Synthesis | CAPROTEC BIOANALYTICS GMBH (DE) | 2002-01-17 | — | — | US | disclosed |
| EP-1073668-A2 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | Köster, Hubert (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055718-A2 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | KOESTER HUBERT (US) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007048-A1 | Solution Phase Biopolymer Synthesis | RNGTT, SGMS1, SPNS2 | PHF8 2810/4885KDM2A 4103/4885KDM4E 4600/4885 |
| US-20020016451-A1 | SOLUTION PHASE BIOPOLYMER SYNTHESIS | RNGTT, SGMS1, SPNS2 | PHF8 2810/4885KDM2A 4103/4885KDM4E 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.