Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17762997 | 0.88 | ECE1 (0.42) | ECE1DNM1PRMT1EPHX2LMNA | |
| SCHEMBL5838840 | 0.85 | PHF8 (0.46) | ECE1DNM1LMNACA12CA1 | |
| SCHEMBL13813061 | 0.82 | CYP2C9 (0.34) | DNM1EPHX2LMNACA12CA9 | |
| SCHEMBL14587045 | 0.81 | HDAC1 (0.48) | LMNATSHRGAAATM | |
| SCHEMBL22383272 | 0.81 | DNM1 (0.42) | ECE1DNM1GAAKDM7APHF8 | |
| SCHEMBL22383271 | 0.81 | GAA (0.44) | ECE1DNM1EPHX2LMNATSHR | |
| SCHEMBL10066553 | 0.81 | ADRA1A (0.48) | ECE1DNM1EPHX2TSHRGAA | |
| SCHEMBL10082396 | 0.81 | CASP2 (0.48) | DNM1EPHX2PHF8 | |
| SCHEMBL16330324 | 0.80 | DNM1 (0.33) | DNM1EPHX2LMNACA12CA1 | |
| SCHEMBL14015355 | 0.78 | CYP2C19 (0.38) | DNM1LMNATSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | MSR1, CD74, CD4 | ECE1 1840/4885DNM1 153/4885PRMT1 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.