SCHEMBL5838893

SCHEMBL5838893

Cc1cccc(C)c1NC(Nc1c(C)cccc1C)C(C)(c1ccccn1)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
FDPS P14324 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 2/20 0.32
SLC40A1 Q9NP59 1/20 0.32
LMNA P02545 1/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
GAA P10253 2/20 0.32
MAPK1 P28482 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SCN8A Q9UQD0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5839167 0.84 SMN1; SMN2 (0.38) SMN1; SMN2L3MBTL1NPC1RAB9AKDM4E
SCHEMBL2018258 0.78 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1NPC1RAB9AKDM4E
SCHEMBL28731708 0.72 KDM4E (0.46) KDM4ESCN8A
SCHEMBL5839742 0.72 SMN1; SMN2 (0.44) SMN1; SMN2L3MBTL1KDM4EALDH1A1LMNA
Hydrochloric Acid SCHEMBL28731715 0.70 KDM4E (0.44) KDM4ESCN8A
SCHEMBL5840008 0.70 SLC40A1 (0.39) SMN1; SMN2L3MBTL1KMT2ASLC40A1LMNA
SCHEMBL19862563 0.68 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL1KDM4EMAPTALDH1A1
SCHEMBL20809866 0.67 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1NPC1RAB9AKDM4E
SCHEMBL22863374 0.67 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1NPC1RAB9AKDM4E
SCHEMBL5407259 0.66 SLC40A1 (0.40) SMN1; SMN2L3MBTL1KMT2ASLC40A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6992034-B2 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2006-01-31 US disclosed
US-20050009690-A1 Catalyst component for olefin polymerization FORMOSA PLASTICS CORPORATIONS, U.S.A. 2005-01-13 US disclosed