Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840008 | 0.82 | SLC40A1 (0.39) | SLC40A1HDAC6SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL16177012 | 0.78 | CCR4 (0.34) | SLC40A1SMN1; SMN2LMNAKMT2AGABRA1 | |
| SCHEMBL19862563 | 0.74 | SMN1; SMN2 (0.47) | HDAC6SMN1; SMN2L3MBTL1LMNACYP1A2 | |
| SCHEMBL17620907 | 0.74 | EGFR (0.42) | LMNAKMT2AGABRA1GABRB2ADORA2A | |
| SCHEMBL28750279 | 0.72 | CETP (0.37) | SLC40A1LMNAKMT2ANMBR | |
| SCHEMBL28959946 | 0.71 | LMNA (0.38) | SMN1; SMN2LMNAKMT2AGABRA1GABRB2 | |
| SCHEMBL14954640 | 0.70 | KMT2A (0.50) | SMN1; SMN2L3MBTL1LMNAKMT2AGABRA1 | |
| SCHEMBL2055586 | 0.70 | SMN1; SMN2 (0.50) | HDAC6SMN1; SMN2L3MBTL1LMNAADORA2A | |
| SCHEMBL21323881 | 0.70 | KDM4E (0.42) | KMT2AADORA2A | |
| SCHEMBL21158254 | 0.69 | GABRA1 (0.41) | SMN1; SMN2LMNAKMT2AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050170950-A1 | Mixed catalyst compositions for the production of polyolefins | W. R. GRACE & CO.-CONN. | 2005-08-04 | — | — | US | claimed |
| EP-1504042-A2 | MIXED CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-02-09 | — | — | EP | claimed |
| WO-2003095508-A2 | MIXED CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2003-11-20 | — | — | WO | claimed |
| US-7166553-B2 | Mixed catalyst compositions for the production of polyolefins | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-6927263-B2 | Catalyst precursor and olefin polymerization processes | UNIVATION TECHNOLOGIES, LLC (US) | 2005-08-09 | — | — | US | disclosed |
| US-20050170950-A1 | Mixed catalyst compositions for the production of polyolefins | W. R. GRACE & CO.-CONN. | 2005-08-04 | — | — | US | disclosed |
| EP-1504042-A2 | MIXED CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20040039140-A1 | Catalyst precursor and olefin polymerization processes | PETERSON THOMAS H (US) | 2004-02-26 | — | — | US | disclosed |
| US-6653417-B2 | Catalyst precursor and olefin polymerization processes | UNIVATION TECHNOLOGIES, LLC | 2003-11-25 | — | — | US | disclosed |
| WO-2003095508-A2 | MIXED CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2003-11-20 | — | — | WO | disclosed |
| US-20030105254-A1 | Catalyst precursor and olefin polymerization processes | UNIVATION TECHNOLOGIES, LLC | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105254-A1 | Catalyst precursor and olefin polymerization processes | PCNA, PARP6, PARP16 | SLC40A1 3432/4885HDAC6 1981/4885SMN1; SMN2 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.