Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838352 | 0.86 | TSHR (0.41) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL1398249 | 0.86 | TSHR (0.41) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL1398234 | 0.86 | TSHR (0.41) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Propanol SCHEMBL27929363 | 0.85 | TSHR (0.53) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Propane SCHEMBL3677972 | 0.85 | TSHR (0.57) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL29375450 | 0.85 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25707 | 0.85 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL16863053 | 0.85 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methane SCHEMBL28897391 | 0.84 | TSHR (0.59) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Ethylene SCHEMBL27572484 | 0.84 | TSHR (0.59) | TSHRKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037954-B2 | Ocular lens material | MENICON CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| EP-1197782-B1 | MATERIAL FOR OCULAR LENS | MENICON CO LTD (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20040039077-A1 | Ocular lens material | MENICON CO., LTD. | 2004-02-26 | — | — | US | disclosed |
| US-6638991-B2 | Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength | MENICON CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20020198280-A1 | Material for ocular lens | MENICON CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1197782-A1 | MATERIAL FOR OCULAR LENS | MENICON CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |